منابع مشابه
Danger Signals in Cardiovascular Disease
1 Department of Internal Medicine I, University Hospital Würzburg, Comprehensive Heart Failure Center, University of Würzburg, Oberdürrbacher Straße 6, 97080 Würzburg, Germany 2 Comprehensive Heart Failure Center, University of Würzburg, Germany 3 Kennedy Institute of Rheumatology, University of Oxford, 65 Aspenlea Road, London W6 8LH, UK 4Laboratory of Experimental Cardiology, University Medic...
متن کاملPreferred levels of auditory danger signals.
An important issue at the design stage of the auditory danger signal for a safety system is the signal audibility under various conditions of background noise. The auditory danger signal should be clearly audible but it should not be too loud to avoid fright, startling effects, and nuisance complaints. Criteria for designing auditory danger signals are the subject of the ISO 7731 (International...
متن کاملMeasuring Railway Signals Passed At Danger
One of the key hazardous events in railways is signals passed at danger (SPAD). SPAD events are relatively common, most with minor consequence. However, SPAD events with catastrophic consequences happen sufficiently often to be a concern within the rail industry. A SPAD event is a precursor to a train collision or derailment; hence there is a strong focus on measuring and reducing their frequen...
متن کاملStaphylococcal Superantigens Spark Host-Mediated Danger Signals
Staphylococcal enterotoxin B (SEB) of Staphylococcus aureus, and related superantigenic toxins produced by myriad microbes, are potent stimulators of the immune system causing a variety of human diseases from transient food poisoning to lethal toxic shock. These protein toxins bind directly to specific Vβ regions of T-cell receptors (TCR) and major histocompatibility complex (MHC) class II on a...
متن کاملDefective viral genomes: critical danger signals of viral infections.
Viruses efficiently block the host antiviral response in order to replicate and spread before host intervention. The mechanism initiating antiviral immunity during stealth viral replication is unknown, but recent data demonstrate that defective viral genomes generated at peak virus replication are critical for this process in vivo. This article summarizes the supporting evidence and highlights ...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Nature Immunology
سال: 2016
ISSN: 1529-2908,1529-2916
DOI: 10.1038/ni.3501